Christian Doppler Laboratory of Molecular Stress Research in Peritoneal Dialysis (MSRPD)

Group Kratochwill
Group Kratochwill

Peritoneal dialysis (PD) is a life-saving renal replacement therapy for more than 200,000 patients worldwide. However, PD causes major morbidity and mortality due to infectious complications and peritoneal membrane failure. From a holistic view, this damage must be regarded as imbalance between PD-related cellular insults and counteracting stress responses. Research at the Medical University of Vienna provided clear evidence for dysfunctional cellular stress responses as a novel pathomechanism in PD. Interventions with cytoprotective PD fluids (PDF) restored peritoneal cellular stress responses, and has been developed to first-use-in-man.

The “Christian Doppler Laboratory for Molecular Stress Research in Peritoneal Dialysis (CDL-MSRPD)” aims to identify molecular stress signatures as surrogate markers of clinical outcome in PD, and to characterize effects and molecular mechanisms of mode of action of PD-protec™, a novel cytoprotective PDF with added alanyl-glutamine, developed to counteract dysfunctional cellular stress responses in PD.

Priv.-Doz. Dipl.-Ing. Dr. Klaus Kratochwill
Head of CD-Lab

News

 
   

This year at the XII EuPA Congress in Santiago de Compostela, Spain (June 16-20th, 2018), more than 250 scientists from all around Europe addressed various topics in proteomics.

 
 

PhD student Florian Wiesenhofer presented results of his dissertation project at the 2018 Young Scientists Symposium

 
 

The 55th European Renal Association – European Dialysis And Transplant Association (ERA-EDTA) Congress was hosted in Copenhagen, Denmark between 24 and 27 May 2018.

 
 

Rebecca Herzog and Klaus Kratochwill attended the 17th Congress of the International Society for Peritoneal Dialysis (ISPD) in Vancouver, Canada from 5 to 8 May, 2018.

 
 

Peritoneal dialysis fluid can be a non-invasive liquid biopsy specimen, but high-abundance proteins mask rarer disease biomarkers.

 
 

Best Submitted PD Abstract at the Annual Dialysis Conference

 
 

CDL-MSRPD researcher Klaus Kratochwill and Rebecca Herzog were presenting their findings to an international audience at the 13th European Peritoneal Dialysis Meeting, which took place on October 4-7, 2017 in Dublin, Ireland. This bi-annual..

 
 

Im Rahmen der gemeinsamen Jahrestagung der Österreichischen Gesellschaften für Nephrologie (ÖGN) und Hypertensiologie (ÖGH), die vom 28.-30. September 2017 in Villach stattgefunden hat, wurde der Vortrag von Dr. Rebecca Herzog zur Publikation..

 
 

This year‘s annual meeting of the ÖGKJ (Österreichische Gesellschaft für Kinder-und Jugendheilkunde (Austrian Society for Pediatric and Adolescent Medicine)) took place in Graz from September 20 to 23. Rebecca Herzog presented the project “Effect of..

 
 

PhD student Katarzyna Bialas presented results of her dissertation project at the 2017 Forum for Young Scientists

 
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